I've had my throat get tired after singing too much, but not actually sore. I know that many accomplished and professional singers use throat soothing products (like "Throat Coat" tea) so it seems possible.
It seems to me, however, that if your throat is actually sore, you probably are singing improperly - shouting more than singing.
Think of it like this, if you talk alot, you might get hoarse and feel your voice or throat is "tired." You won't automatically get a sore throat, though, unless you're screaming.
I'd suggest that you warm up your voice before singing a lot, and drink tea with honey.
Also, when you're trying for power or volume in your singing, don't push it out from your throat but from your lungs and diaphragm
Google: Singing+Method and you'll find TONs of resources you can buy to help you sing properly.
Happy singing!